- Children with Marcellus
Octavia and her first husband had one son and two daughters born late in their marriage:
- Claudia Marcella Major
- Claudia Marcella Minor
- Children with Mark Antony
Octavia and Mark Antony had two daughters by their marriage (her second, his fourth), and both were the ancestors of later Roman emperors.
- Antonia Major: also known as Julia Antonia Major, grandmother to Emperor Nero.
- Antonia Minor: also known as Julia Antonia Minor, mother to Emperor Claudius, grandmother to Emperor Caligula, and great-grandmother to Emperor Nero.