Kuniyoshi was part of the Utagawa school of artists.
The range of Kuniyoshi's subjects included landscapes, beautiful women, Kabuki actors, cats, and mythical animals. He is known images of the battles of samurai and legendary heroes. His work was affected by Western art and caricature.
His work influenced Toyohara Chikanobu.
Takashi Murakami credits the influence of Kuniyoshi in his work.