Roderick MacKinnon

Roderick MacKinnon
Roderick MacKinnon, M.D..jpg
Born(1956-02-19)19 February 1956
Burlington, Massachusetts, USA
NationalityUnited States
Alma materBrandeis University
AwardsNobel Prize in Chemistry (2003),
Albert Lasker Award for Basic Medical Research (1999),
Louisa Gross Horwitz Prize (2003)
Scientific career

Roderick MacKinnon (born 19 February 1956) is a professor of Molecular Neurobiology and Biophysics at Rockefeller University. He won the Nobel Prize in Chemistry together with Peter Agre in 2003 for his work on the structure and operation of ion channels.[1][2][3]


Early life and education

MacKinnon was born in Burlington, Massachusetts and initially attended the University of Massachusetts Boston. MacKinnon then transferred to Brandeis University after one year, and there he received a bachelor's degree in biochemistry in 1978, studying calcium transport through the cell membrane for his honors thesis in Christopher Miller's laboratory. It was also at Brandeis where MacKinnon met his future wife and working-colleague Alice Lee.[4]

After receiving his degree from Brandeis, MacKinnon entered medical school at Tufts University.[3] He got his M.D. in 1982 and received training in Internal Medicine at Beth Israel Hospital in Boston. He did not feel satisfied enough with the medical profession, so in 1986 he returned to Christopher Miller's laboratory at Brandeis for postdoctoral studies.[4]


In 1989 he was appointed assistant professor at Harvard University where he studied the interaction of the potassium channel with a specific toxin taken from scorpion venom. He learned how to purify proteins and to use X-ray crystallography. In 1996, he moved to Rockefeller University as a professor and head of the Laboratory of Molecular Neurobiology and Biophysics. There, he started to work on the structure of the potassium channel. These channels are of particular importance to the nervous system and the heart. The channels enable potassium ions to cross the cell membrane.

Other Languages
беларуская: Родэрык Мак-Кінан
Bahasa Indonesia: Roderick MacKinnon
Nederlands: Roderick MacKinnon
Plattdüütsch: Roderick MacKinnon
português: Roderick MacKinnon
slovenčina: Roderick MacKinnon
српски / srpski: Родерик Макинон
татарча/tatarça: Родерик Маккиннон
українська: Родерік Маккінон
Tiếng Việt: Roderick MacKinnon