The Muldentalkreis is a district in the Free State of Saxony, Germany.
The district was formed in 1994 when the two old districts of Grimma and Wurzen were joined together. A few municipalities from other districts around Bad Lausick were added as well.
The district is named after its major river, the Mulde - the name German: Muldental means English: Valley of the Mulde. The Mulde is starts in the south of the district where two smaller rivers, the Freiberger Mulde and the Zwickauer Mulde join.