Map of South Carolina highlighting "The Upstate" region.
The Upstate is the region in the westernmost part of South Carolina, United States, also known as the Upcountry, which is the historical term. Although loosely defined among locals, the general definition includes the ten counties of the commerce-rich I-85 corridor in the northwest corner of South Carolina. This definition coincides with the Greenville–Spartanburg–Anderson, SC Combined Statistical Area, as first defined by the Office of Management and Budget in 2015, and maintained as of 2017. The region's population was 1,347,112 as of 2016. Situated between Atlanta and Charlotte, the Upstate is the fastest-growing region of South Carolina, and is the geographical center of the Charlanta mega-region. After BMW's initial investment, foreign companies, including others from Germany, have a substantial presence in the Upstate; several large corporations have established regional, national, or continental headquarters in the area. Greenville is the largest city in the region with a population of 67,453 and an urban-area population of 400,492, and it is the base of most commercial activity. Spartanburg, followed by Anderson, are next in population.