After the withdrawal of the Greek forces in Asia Minor and the expulsion of the Ottoman sultan by the Turkish army under the command of Mustafa Kemal Atatürk, the Ankara-based Kemalist government of the Turkish national movement rejected the territorial losses imposed by the 1920 Treaty of Sèvres previously signed by the Ottoman Empire. Britain had sought to undermine Turkish influence in Mesopotamia and Kirkuk by seeking the division of Kurdish populated regions in Eastern Anatolia, but secular Kemalist rhetoric relieved some of the international concerns about the future of the Armenian community that had survived the 1915 Armenian genocide and support for Kurdish self determination similarly declined. Under the Treaty of Lausanne, signed in 1923, Eastern Anatolia became part of modern day Turkey, in exchange for Turkey's relinquishing Ottoman-era claims to the oil-rich Arab lands.
Negotiations were undertaken during the Conference of Lausanne, where İsmet İnönü was the chief negotiator for Turkey. Lord Curzon, the British Foreign Secretary of that time, was the chief negotiator for the Allies, while Eleftherios Venizelos negotiated on behalf of Greece. The negotiations took many months. On 20 November 1922, the peace conference was opened and after strenuous debate was interrupted by Turkish protest on 4 February 1923. After reopening on 23 April, and following more protests by the Turks and tense debates, the treaty was signed on 24 July as a result of eight months of arduous negotiation. The Allied delegation included U.S. Admiral Mark L. Bristol, who served as the United States High Commissioner and championed Turkish efforts.