On 10 March 1918, Therese Neumann was partially paralyzed after falling off a stool while attending to a fire in her uncle's barn. She sustained more falls and injuries during this period. After one particular fall she claimed to have lost much of her eyesight, and in 1919 she claimed to have been blinded completely. Bedridden, she reportedly developed horrible bed sores that sometimes exposed bone.
Therese reported that her eyesight was restored on 29 April 1923—the day Therese of Lisieux was beatified in Rome. Therese Neumann had been praying novenas in advance of this day. On 17 May 1925 Therese of Lisieux was fully canonized as a saint in the Catholic Church. Therese Neumann said the saint called to her and then cured her of her paralysis and bed sores.
On 7 November 1925 Neumann took to her bed again, and on 13 November claimed to have been diagnosed with appendicitis. According to her account, while prepared for surgery she convulsed violently and stared at the ceiling finally saying, "Yes." She asked her family to take her to the church to pray immediately. She then announced that she had been cured of all traces of appendicitis.
Physicians and skeptics have disputed Neumann's claims of miraculous cures. According to skeptical investigator Joe Nickell on one occasion Neumann claimed to have healed herself from blindness, but whilst "blind" she was examined and her pupils responded normally to light. Nickell suspected that Neumann's claims were performed by "hysterical hypochondria" or "outright fakery".