Life and career
Pyfrom was born in Tampa, Florida. He is of Welsh, English, Dutch, Italian, German, Hungarian, French and Irish descent. "Caminiti", his middle name, is the maiden name of his mother, Gail. Pyfrom has an older brother named Christopher and a younger sister named Amber.
He is known for his recurring role as Andrew Van de Kamp, the gay son of Bree Van de Kamp (Marcia Cross) and the late Rex Van de Kamp (Steven Culp) on ABC's Desperate Housewives. He played the role, as a recurring guest appearance, throughout the show's first season (2004–2005). After appearing in the entire second season as a supporting cast member (for which he was credited in the opening credits), and appearing in the third season and fourth season, he returned in the fifth season as a full-fledged series regular. Shawn appeared in the Walt Disney Pictures film The Shaggy Dog (2006) opposite Tim Allen and Kristin Davis, and the film The Darkroom (2007) opposite Erin Foster. In 2009, Pyfrom left Desperate Housewives as a series regular, but continued to make frequent guest appearances, including the series finale.
In the wake of Philip Seymour Hoffman's death in 2014 by overdose, Pyfrom admitted five-month recovery as of February 2014 from drug addiction and alcoholism.