SHOT's statistical data has been used to decrease
bacterial infections through better skin cleansing procedures and the incidence of life-threatening
transfusion-related acute lung injury (TRALI) in the UK, by discouraging the use of
fresh frozen plasma from female donors.
 The cause of TRALI is not fully understood, and may have more than one mechanism,
 but most cases are associated with transfusion of plasma or other blood products that contain some
antibodies that the donor developed during
 Not using plasma donation from female donors for transfusions eliminates the risk of exposing the recipient to pregnancy-related antibodies, and therefore reduces the risk of TRALI.
 The collected information has also provided evidence to support the pre-existing practice of leukodepletion (depleting the number of
leukocytes, or white blood cells, from the product) to reduce the risk of
transfusion-associated graft-versus-host disease and
post-transfusion purpura in immunocompromised patients.
SHOT's data has also focused attention on
human errors, with the result that staff training and procedures have been improved. For example, SHOT's data demonstrated that increasing the use of wristbands for patient identification and portable, bedside
barcode readers reduced the risk of an error caused by