After unsuccessfully seeking the Republican presidential nomination in 1960, 1964, and 1968, Rockefeller served as Vice President of the United States under President Gerald R. Ford, who ascended to the presidency following the August 1974 resignation of Richard Nixon over the Watergate scandal. Rockefeller was the second vice president appointed to the position under the 25th Amendment, following Ford himself. Rockefeller decided not to join the 1976 Republican ticket with Ford, which ultimately went to Bob Dole. He retired from politics in 1977, and died two years later.
As a businessman, Rockefeller was president and later chair of Rockefeller Center, Inc., and he formed the International Basic Economy Corporation in 1947. Rockefeller assembled a significant art collection and promoted public access to the arts. He served as trustee, treasurer, and president of the Museum of Modern Art, and founded the Museum of Primitive Art in 1954. In the area of philanthropy, he founded the Rockefeller Brothers Fund in 1940 with his four brothers and established the American International Association for Economic and Social Development in 1946.