Part I: Join or Die (1770–1774)
Episode 1 opens in Boston 1770 on the cold winter night of the Boston Massacre. It portrays John Adams arriving at the scene following the gunshots from British soldiers firing upon a mob of Boston citizens. Adams, a respected lawyer in his mid-30s known for his dedication to the law and justice, is sought as defense counsel for the accused Redcoats. Their commander, Captain Thomas Preston, asks him to defend them in court. Reluctant at first, he agrees despite knowing this will antagonize his neighbors and friends. Adams is depicted to have taken the case because he believed everyone deserves a fair trial and he wanted to uphold the standard of justice. Adams' cousin Samuel Adams is one of the main colonists opposed to the actions of the British government. He is one of the executive members of the Sons of Liberty, an anti-British group of agitators. Adams is depicted as a studious man doing his best to defend his clients. The show also illustrates Adams' appreciation and respect for his wife, Abigail. In one scene, Adams is shown having his wife proofread his summation as he takes her suggestions. After many sessions of court, the jury returns verdicts of not guilty of murder for each defendant. The episode also illustrates the growing tensions over the Coercive Acts ("Intolerable Acts"), and Adams' election to the First Continental Congress.
Part II: Independence (1774–1776)
The second episode covers the disputes among the members of the Second Continental Congress toward declaring independence from Great Britain as well as the final drafting of the Declaration of Independence. At the Continental Congresses Adams is depicted as the lead advocate for independence. He is in the vanguard in establishing that there is no other option than to break off and declare independence. He is also instrumental in the selection of then-Colonel George Washington as the new head of the Continental Army.
However, in his zeal for immediate action, he manages to alienate many of the other founding fathers, going so far as to insult John Dickinson, who is for conciliation to the Crown, implying that the man suffers from a religiously based moral cowardice. Later, Benjamin Franklin quietly chastens Adams, saying it is "perfectly acceptable to insult a man in private. He may even thank you for it afterwards. But when you do it in public, they tend to think you are serious." This points out Adams' primary flaw: his bluntness and lack of gentility toward his political opponents, one that would make him many enemies and which would eventually plague his political career. It would also, eventually, contribute to historians' disregard for his many achievements. The episode also shows how Abigail copes with issues at home as her husband was away much of the time participating in the Continental Congress. She employs the use of then pioneer efforts in the field of preventative medicine and inoculation against smallpox for herself and the children.
Part III: Don't Tread on Me (1777–1781)
In Episode 3, Adams travels to Europe with his young son John Quincy during the Revolutionary War seeking alliances with foreign nations, during which the ship transporting them battles a British frigate. It first shows Adams' embassy with Benjamin Franklin in the court of Louis XVI of France. The old French nobility, who are in the last decade before being consumed by the French Revolution, are portrayed as effete and decadent. They meet cheerfully with Franklin, seeing him as a romantic figure, little noting the democratic infection he brings with him. Adams, on the other hand, is a plain spoken and faithful man, who finds himself out of his depth surrounded by an entertainment- and sex-driven culture among the French elite. Adams finds himself at sharp odds with Benjamin Franklin, who has adapted himself to the French, seeking to obtain by seduction what Adams would gain through histrionics. Franklin sharply rebukes Adams for his lack of diplomatic acumen, describing it as a "direct insult followed by a petulant whine". Franklin soon has Adams removed from any position of diplomatic authority in Paris. His approach is ultimately successful and was to result in the conclusive Franco-American victory at Yorktown.
Adams, chastened and dismayed but learning from his mistakes, then travels to the Dutch Republic to obtain monetary support for the Revolution. Although the Dutch agree with the American cause, they do not consider the new union a reliable and credit-worthy client. Adams ends his time in the Netherlands in a state of progressive illness, having sent his son away as a diplomatic secretary to the Russian Empire.
Part IV: Reunion (1781–1789)
The fourth episode shows John Adams being notified of the end of the Revolutionary War and the defeat of the British. He is then sent to Paris to negotiate the Treaty of Paris in 1783. While overseas, he spends time with Benjamin Franklin and Thomas Jefferson and Abigail visits him. Franklin informs John Adams that he was appointed as the first American Ambassador to Great Britain and thus has to relocate to London. John Adams is poorly received by the British during this time—he is the representative for a recently hostile power, and represents in his person what many British at the time regarded as a disastrous end to its early Empire. He meets with his former sovereign, George III, and while the meeting is not a disaster, he is excoriated in British newspapers. In 1789, he returns to Massachusetts for the first presidential election and he and Abigail are reunited with their children, now grown. George Washington is elected the first President of the United States and John Adams as the first Vice President.
Initially, Adams is disappointed and wishes to reject the post of Vice President because he feels there is a disproportionate number of electoral votes in favor of George Washington (Adams' number of votes pales in comparison to those garnered by Washington). In addition, John feels the position of Vice President is not a proper reflection of all the years of service he has dedicated to his nation. However, Abigail successfully influences him to accept the nomination.
Part V: Unite or Die (1788–1797)
The fifth episode begins with Vice President John Adams presiding over the Senate and the debate over what to call the new President. It depicts Adams as frustrated in this role: His opinions are ignored and he has no actual power, except in the case of a tied vote. He's excluded from George Washington's inner circle of cabinet members, and his relationships with Thomas Jefferson and Alexander Hamilton are strained. Even Washington himself gently rebukes him for his efforts to "royalize" the office of the Presidency, although Washington values Adams' counsel in other areas, considering him to be "reasonable company" when compared with Jefferson and Hamilton. A key event shown is the struggle to enact the Jay Treaty with Britain, which Adams himself must ratify before a deadlocked Senate (although historically his vote was not required). The episode concludes with his inauguration as the second president—and his subsequent arrival in a plundered executive mansion.
Part VI: Unnecessary War (1797–1801)
The sixth episode covers Adams's term as president and the rift between the Hamilton-led Federalists and Jefferson-led Republicans. Adams's neutrality pleases neither side and often angers both. His shaky relationship with vice president Thomas Jefferson worsens after taking defensive actions against the French because of failed diplomatic attempts and the signing of the Alien and Sedition Acts. Adams also alienates himself from the anti-French Alexander Hamilton after taking all actions possible to prevent a war with France. He disowns his son Charles, who soon dies as an alcoholic vagrant. Adams sees success late in his Presidency with his campaign of preventing a war with France, but his success is clouded after losing the presidential election of 1800. After receiving so much bad publicity while in office, Adams lost the election against his Vice-President, Thomas Jefferson, and runner-up Aaron Burr (both from the same party). Adams leaves the Presidential Palace (now known as the White House) in March 1801 and retires to his personal life in Massachusetts.
Part VII: Peacefield (1803–1826)
The final episode covers Adams's retirement years. His home life at Peacefield is full of pain and sorrow as his daughter, Nabby, dies of breast cancer and Abigail succumbs to typhoid fever. Adams does live to see the election of his son, John Quincy, as president, but is too ill to attend the inauguration. Adams and Jefferson are reconciled through correspondence in their last years. Both die hours apart on July 4, 1826, the 50th anniversary of the Declaration of Independence. Jefferson was 83, Adams was 90.