Heart valve

Heart valves
CG Heart.gif
Valves of the heart in motion, the front wall of the heart is removed in this image.
Details
SystemCardiovascular
Identifiers
MeSHD006351
FMA7110
Anatomical terminology

A heart valve normally allows blood to flow in only one direction through the heart. The four valves commonly represented in a mammalian heart determine the pathway of blood flow through the heart. A heart valve opens or closes incumbent on differential blood pressure on each side.[1][2][3]

The four main valves in the heart are:

  • The two atrioventricular (AV) valves, the mitral valve (bicuspid valve), and the tricuspid valve, which are between the upper chambers (atria) and the lower chambers (ventricles).
  • The two semilunar (SL) valves, the aortic valve and the pulmonary valve, which are in the arteries leaving the heart.

The mitral valve and the aortic valve are in the left heart; the tricuspid valve and the pulmonary valve are in the right heart.

There are also the coronary sinus and the inferior vena cava valves.

Structure

Structure of the heart valves
Blood flow through the valves

The heart valves and the chambers are lined with endocardium. Heart valves separate the atria from the ventricles, or the ventricles from a blood vessel. Heart valves are situated around the fibrous rings of the cardiac skeleton. The valves incorporate leaflets or cusps, which are pushed open to allow blood flow and which then close together to seal and prevent backflow. The mitral valve has two cusps, whereas the others have three. There are nodules at the tips of the cusps that make the seal tighter.

The pulmonary valve has left, right, and anterior cusps.[4] The aortic valve has left, right, and posterior cusps.[5] The tricuspid valve has anterior, posterior, and septal cusps; and the mitral valve has just anterior and posterior cusps.

Atrioventricular valves

3D - loop of a heart viewed from the apex, with the apical part of the ventricles removed and the mitral valve clearly visible. Due to missing data, the leaflets of the tricuspid and aortic valves are not clearly visible, but the openings are; the pulmonary valve is not visible. On the left are two standard 2D views (taken from the 3D dataset) showing tricuspid and mitral valves (above) and aortal valve (below).

These are the mitral and tricuspid valves, which are situated between the atria and the ventricles and prevent backflow from the ventricles into the atria during systole. They are anchored to the walls of the ventricles by chordae tendineae, which prevent the valves from inverting.

The chordae tendineae are attached to papillary muscles that cause tension to better hold the valve. Together, the papillary muscles and the chordae tendineae are known as the subvalvular apparatus. The function of the subvalvular apparatus is to keep the valves from prolapsing into the atria when they close. The subvalvular apparatus has no effect on the opening and closure of the valves, however, which is caused entirely by the pressure gradient across the valve. The peculiar insertion of chords on the leaflet free margin, however, provides systolic stress sharing between chords according to their different thickness.[6]

The closure of the AV valves is heard as lub, the first heart sound (S1). The closure of the SL valves is heard as dub, the second heart sound (S2).

The mitral valve is also called the bicuspid valve because it contains two leaflets or cusps. The mitral valve gets its name from the resemblance to a bishop's mitre (a type of hat). It is on the left side of the heart and allows the blood to flow from the left atrium into the left ventricle.

During diastole, a normally-functioning mitral valve opens as a result of increased pressure from the left atrium as it fills with blood (preloading). As atrial pressure increases above that of the left ventricle, the mitral valve opens. Opening facilitates the passive flow of blood into the left ventricle. Diastole ends with atrial contraction, which ejects the final 30% of blood that is transferred from the left atrium to the left ventricle. This amount of blood is known as the end diastolic volume (EDV), and the mitral valve closes at the end of atrial contraction to prevent a reversal of blood flow.

The tricuspid valve has three leaflets or cusps and is on the right side of the heart. It is between the right atrium and the right ventricle, and stops the backflow of blood between the two.

Semilunar valves

The aortic and pulmonary valves are located at the base of the aorta and the pulmonary trunk respectively. These are also called the "semilunar valves". These two arteries receive blood from the ventricles and their semilunar valves permit blood to be forced into the arteries, and prevent backflow from the arteries into the ventricles. These valves do not have chordae tendineae, and are more similar to the valves in veins than they are to the atrioventricular valves. The closure of the semilunar valves causes the second heart sound.

The aortic valve, which has three cusps, lies between the left ventricle and the aorta. During ventricular systole, pressure rises in the left ventricle and when it is greater than the pressure in the aorta, the aortic valve opens, allowing blood to exit the left ventricle into the aorta. When ventricular systole ends, pressure in the left ventricle rapidly drops and the pressure in the aorta forces aortic valve to close. The closure of the aortic valve contributes the A2 component of the second heart sound.

The pulmonary valve (sometimes referred to as the pulmonic valve) lies between the right ventricle and the pulmonary artery, and has three cusps. Similar to the aortic valve, the pulmonary valve opens in ventricular systole, when the pressure in the right ventricle rises above the pressure in the pulmonary artery. At the end of ventricular systole, when the pressure in the right ventricle falls rapidly, the pressure in the pulmonary artery will close the pulmonary valve. The closure of the pulmonary valve contributes the P2 component of the second heart sound. The right heart is a low-pressure system, so the P2 component of the second heart sound is usually softer than the A2 component of the second heart sound. However, it is physiologically normal in some young people to hear both components separated during inhalation.

Development

In the developing heart, the valves between the atria and ventricles, the bicuspid and the tricuspid valves, develop on either side of the atrioventricular canals.[7] The upward extension of the bases of the ventricles causes the canal to become invaginated into the ventricle cavities. The invaginated margins form the rudiments of the lateral cusps of the AV valves. The middle and septal cusps develop from the downward extension of the septum intermedium.

The semilunar valves (the pulmonary and aortic valves) are formed from four thickenings at the cardiac end of the truncus arteriosus.[7] These thickenings are called endocardial cushions.[citation needed] The truncus arteriosus is originally a single outflow tract from the embryonic heart that will later split to become the ascending aorta and pulmonary trunk. Before it has split, four thickenings occur. There are anterior, posterior, and two lateral thickenings. A septum begins to form between what will later become the ascending aorta and pulmonary tract. As the septum forms, the two lateral thickenings are split, so that the ascending aorta and pulmonary trunk have three thickenings each (an anterior or posterior, and half of each of the lateral thickenings). The thickenings are the origins of the three cusps of the semilunar valves. The valves are visible as unique structures by the ninth week. As they mature, they rotate slightly as the outward vessels spiral, and move slightly closer to the heart.[7]

Other Languages
العربية: صمام قلبي
bosanski: Srčani zalisci
čeština: Chlopeň
Deutsch: Herzklappe
emiliàn e rumagnòl: Vàrvora dal cōr
Esperanto: Korvalvo
فارسی: دریچه قلب
français: Valve cardiaque
Bahasa Indonesia: Katup jantung
עברית: מסתמי הלב
қазақша: Клапан
македонски: Срцев залисток
Nederlands: Hartklep
नेपाली: भल्भ
norsk nynorsk: Hjarteklaff
português: Valva cardíaca
српски / srpski: Срчани залисци
svenska: Hjärtklaff
українська: Клапани серця
Tiếng Việt: Van tim
中文: 心瓣