Fisichella won three races in his Formula One career, the first of which was at the chaotic 2003 Brazilian Grand Prix, a race abandoned for safety reasons with 15 laps remaining. After several days of confusion regarding rules and technicalities, Fisichella was eventually declared the winner in the following week, and collected his trophy in an unofficial ceremony at the following race. He was brought into the Renault team to replace fellow ItalianJarno Trulli, and won his first race with the team in Australia in 2005. However, after that race it was his teammate, the Spanish driver Fernando Alonso, that would win the greater share of races for Renault. Although highly rated as a driver, Fisichella was unable to keep pace with eventual champion Alonso, managing just one further race win following his debut. Outside of driving, he has backed his own GP2 team, FMS International.
On 17 June 2012 Fisichella won the GTE Pro division of the Le Mans 24hrs for AF Corse and followed this up with the Manufacturers' title in the WEC at the end of the season.