Edwin G. Krebs

Edwin Gerhard Krebs
Edwin G. Krebs.jpg
Edwin Gerhard Krebs
Born(1918-06-06)June 6, 1918
DiedDecember 21, 2009(2009-12-21) (aged 91)
NationalityUnited States
Alma materUniversity of Illinois at Urbana-Champaign (B.S.),
Washington University in St. Louis (M.D.)
AwardsLouisa Gross Horwitz Prize (1989)
Welch Award in Chemistry (1991)
Nobel Prize in Physiology or Medicine (1992)
Scientific career
Fieldsbiochemistry
InstitutionsUniversity of Washington, Seattle
University of California, Davis

Edwin Gerhard Krebs (June 6, 1918 – December 21, 2009) was an American biochemist. He received the Albert Lasker Award for Basic Medical Research and the Louisa Gross Horwitz Prize of Columbia University in 1989 together with Alfred Gilman and, together with his collaborator Edmond H. Fischer, was awarded the Nobel Prize in Physiology or Medicine in 1992 for describing how reversible phosphorylation works as a switch to activate proteins and regulate various cellular processes.

Edwin Krebs is not to be confused with Hans Adolf Krebs (1900–1981), who was also a Nobel Prize–winning biochemist and who discovered the citric acid cycle, which is also known as the Krebs cycle.

Early life and education

Krebs was born in Lansing, Iowa, the third child of William Carl Krebs, a Presbyterian minister and Louise Helen (Stegeman) Krebs. The family moved frequently due to the nature of his father's work, though they settled in Greenville, Illinois when Krebs was six and remained there until his father's unexpected death in 1933. Louise Krebs decided to move her family to Urbana, Illinois, where Krebs's elder brothers were attending the University of Illinois at Urbana-Champaign. Krebs attended Urbana High School, and enrolled at the University of Illinois at Urbana-Champaign in 1936. In his fourth year of study Krebs had decided to either pursue a higher degree in organic chemistry or study medicine. Receiving a scholarship to attend Washington University School of Medicine in St. Louis, he chose the latter.

The School of Medicine afforded Krebs the opportunity to train as a physician as well as to gain experience in medical research. Following graduation in 1943, he undertook an 18-month residency at Barnes Hospital in St. Louis and then went on active duty as a medical officer in the Navy. Krebs was discharged from the Navy in 1946 and was unable to immediately return to hospital work; he was advised to study basic science instead. He chose to study biochemistry and was postdoctoral fellow to Carl and Gerty Cori, working on the interaction of protamine with rabbit muscle phosphorylase. At the completion of his two years' study, Krebs decided to continue his career as a biochemist.

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العربية: إدوين كريبس
беларуская: Эдвін Крэбс
čeština: Edwin G. Krebs
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қазақша: Эдвин Кребс
Kiswahili: Edwin Krebs
پنجابی: ایڈون کربز
Plattdüütsch: Edwin Gerhard Krebs
português: Edwin Krebs
русский: Кребс, Эдвин
Simple English: Edwin G. Krebs
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українська: Едвін Кребс
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