Drugs and devices in Year Zero

Year Zero
Art Is Resistance.svg

an alternate reality game by
Nine Inch Nails
and 42 Entertainment


Campaign timeline


Year Zero album
"Survivalism" single
"Capital G" single
Beside You in Time HD DVD and BD
Year Zero Remixed album



Characters and organizations

Drugs and devices

This is a comprehensive list of drugs, viruses, and body augmentations from the Year Zero alternate reality game by Nine Inch Nails and 42 Entertainment. The Year Zero alternate reality game, and its accompanying concept album of the same name, criticizes the United States government's policies as of 2007,[1] projecting a dystopian vision of its impact on the state of events in 2022. The game has been underway since roughly February 12, 2007 and is expected to continue for approximately eighteen months.[2]


A psychotropic drug released into American water supplies, purported to reduce the risk of bioterrorism by bolstering the immune system. However, the creator of I am Trying to Believe claims to have debunked these myths as a conspiracy; parepin is actually a sedative, known to affect serotonin and dopamine levels. The drug is also known to reduce the sex drive of anyone who has ingested the drug, cause facial ticks and constipation, as well as subduing resistance to authority. Some people under the influence of the drug are known to have had hypnagogic hallucinations, particularly that of The Presence.
Opal (Hycephamitamyn-η)
A new drug, supposedly "the new crack", as it is cheaper to distribute and more widely available. Dispensed in a small, pressurized glass tube with a syringe on one end, the drug, which appears as a black liquid, is dropped or injected directly into the eyes, or absorbed through the skin in powdered form with the aid of a solvent. While initially developed as a hallucinogenic sedative, it has become popular as a recreational drug, with users often experiencing an intense, often religious, state of mind. At least one website notes a correlation between Opal use and sightings of The Presence.
In a top-secret internal memo from Cedocore found here, Opal is revealed to be a product of Cedocore, via a subsidiary company by the name of "Wantzen-Tabard-Boutier", being distributed through organized crime.
Blue pills
Referenced in Be the Hammer [1]. Nicknamed "die-agra", these pills are given to soldiers to reintroduce the aggression lost by taking Parepin. They are said to help "keep you frosty and get your soldier on."
Red pills
Also referenced in Be the Hammer [2]. Nicknamed "blisters", "bloody mary", and "jerk", these pills seem to be a more extreme version of the Blue pills, given to only the best soldiers. They are said to "erase the line between killing and fucking. Some of the damage is permanent." Due to the cryptic nature of its mention, it is unclear whether soldiers are either not allowed to see their families after taking the Red pills, or are not warned of the propensity of the prescribed user to become lethally violent during sex, but either way are told the drug's side effects only after they are given the pill.
  • Anphylox
  • Amproprax
  • Avoprem
  • Niraderm
  • Phenylpro (believed to be Phenethylamine)
  • Prozira
  • Sariferm
  • Xarylax
  • Zalaflo
  • Zynacor