Attanasio was born in Milan.
After studies at the Academy of Arts of Milan, Dino Attanasio started to work in illustration and animation in the 1940s. He moved to Belgium in 1948 with his brother Gianni, also an artist. Shortly after his arrival, the young artist got in contact with Tintin magazine, for which he drew some illustrations, and decided to devote himself to comics. In the 1950s, he published
Criche e Croc in the Italian magazine Il Giornalino and Fanfan et Polo in La Libre Belgique with scripts by Jean-Michel Charlier and then René Goscinny. At that time, he also worked for Spirou magazine with some contributions to Les Belles Histoires de l'Oncle Paul. In 1954, he published "
Pastis et Dynamite" in
He became popular in the late 1950s and 1960s thanks to The Adventures of
Signor Spaghetti, a comic series he created with Goscinny, published in Tintin after 1957.
From 1959 à 1962 he published in Femmes d'aujourd'hui the comics series version of Les Aventures de Bob Morane, a series of novels written by Henri Vernes and for which he made some illustrations and art covers in the Marabout Junior collection. However, he is replaced for this job by
Gérald Forton. Then, from 1961 to 1968, he took over the series Modeste et Pompon, originally created by Franquin.
After his departure from Tintin in 1968, Attanasio started working for the Dutch market, creating the series
Johnny Goodbye with Martin Lodewijk and
Patty Klein for Eppo and
Pep, with Bandoneon (with Delporte) in Pep and with
De Macaroni's (with Dick Matena), but also for Italian magazines with "
Ambroise et Gino" in Corriere dei piccoli. From 1974 to 1986 he took on the Spaghetti series again in Formule 1, published in albums by Archers. In 1991 Attanasio created a comic adaptation of Boccaccio's literary classic Decameron with his son, published by
Lefrancq. In 1994, he took over the series Bob Morane for one story only. Since then, new works have made rarer and some have publishers rediscovered some of his works, as Carnets de route in 1999 by
Point Image and since 2002 some shorts stories originally published in Tintin, by