|ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR, adrenoceptor beta 2|
|External IDs||109690 87938 30948 ADRB2 |
|Gene location (Mouse)|
|Chr.||Chromosome 18 (mouse)|
|Band||18 E1|18 35.1 cM||Start||62,177,817 bp|
|Chr 18: 62.18 – 62.18 Mb|
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via adenylate cyclase stimulation through trimeric Gs proteins, increased cAMP, and downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation.
The official symbol for the human gene encoding the β2 adrenoreceptor is ADRB2.