Beta-2 adrenergic receptor

ADRB2
2RH1.png
Available structures
5JQH

IdentifiersADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR, adrenoceptor beta 2External IDs109690 87938 30948 ADRB2
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for ADRB2
Genomic location for ADRB2
Band5q32, 5q32Start148,825,245 bp[1]
End148,828,687 bp[1]
RNA expression pattern
PBB GE ADRB2 206170 at fs.png
More reference expression data
OrthologsSpeciesHumanMouse11555

ENSMUSG00000045730

Chr 18: 62.18 – 62.18 MbPubMed search[3][4]Wikidata
View/Edit HumanView/Edit Mouse

The beta-2 adrenergic receptor2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via adenylate cyclase stimulation through trimeric Gs proteins, increased cAMP, and downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation.[5]

The official symbol for the human gene encoding the β2 adrenoreceptor is ADRB2.[6]

Other Languages
Cymraeg: ADRB2
српски / srpski: Beta-2 adrenergički receptor
srpskohrvatski / српскохрватски: Beta-2 adrenergički receptor
українська: ADRB2